RANKL Polyclonal Antibody, 100ul[BT-AP07786] Immunoassays Basic helix-loop-helix (bHLH) transcription factors

Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation

CNKSR2 encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras

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where it is differentially expressed during differentiation

together with other proteins

RANKL Polyclonal Antibody, 100ul[BT-AP07786] Immunoassays Basic helix-loop-helix (bHLH) transcription factorsThis gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss.