TFE3 Polyclonal Antibody, 100ul Vector Construction Isoform 1 and isoform 2

Isoform 1 and isoform 2 function in nuclear receptor coactivation

is the first rate limiting enzyme of glutathione synthesis

This isozyme has a high preference for lipid hydroperoxides and protects cells against membrane lipid peroxidation and cell death

Mutations in this gene also cause schizophrenia type 15

Glutathione S-transferase theta-1 encoded by GSTT1 is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds

TFE3 Polyclonal Antibody, 100ul Vector Construction Isoform 1 and isoform 2TFE3 (transcription factor binding to IGHM enhancer 3) encodes a basic helix loop helix domain containing transcription factor that binds MUE3 type E box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF beta) signaling. TFE3 may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins.