EPAS-1 Polyclonal Antibody, 100ul Cell Separation and Collection This gene is known to

This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma

immunologic crossreactivity and physiologic function

stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways

A stop solution is added to terminate the reaction

In eukaryotes

EPAS-1 Polyclonal Antibody, 100ul Cell Separation and Collection This gene is known toEPAS1 encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The endothelial PAS domain protein 1 contains a basic helix loop helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.