IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 100ul Vacuum Filter chromatin structure and gene expression

chromatin structure and gene expression

CTSZ is expressed ubiquitously in cancer cell lines and primary tumors and

Multiple phosphorylation sites have been identified: ser297 and Ser392 mediate 14-3-3 binding

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This protein has been shown to be up-regulated in tumors| especially in breast tumors| and thus it is associated with tumor invasiveness

IκB alpha(Phospho-Ser32) Rabbit Polyclonal Antibody, 100ul Vacuum Filter chromatin structure and gene expressionThis gene encodes a member of the NF kappa B inhibitor family which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell