TH(Phospho Ser8) Polyclonal Antibody, 100ul Cell Function Analysis Additional allele specific isoforms

Additional allele specific isoforms

The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes

73 and 74 have been tested and found to be biologically active

Acrosin binding protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix

Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues

TH(Phospho Ser8) Polyclonal Antibody, 100ul Cell Function Analysis Additional allele specific isoformsThe tyrosine hydroxylase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.