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MARCH1 Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) It is enriched in the

SKU: 29438613678

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MARCH1 Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) It is enriched in theMARCH1 (membrane associated ring CH type finger 1) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the

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Description

It is enriched in the basement membrane of muscles at the neuromuscular junctions

The kinases of these signaling cascades are highly conserved

interacting with other transcription factors through a tetrapeptide domain in its C-terminus

The CD163 molecule like 1 contains twelve SRCR domains

An important paralog of this gene is IQGAP1

MARCH1 Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) It is enriched in theMARCH1 (membrane associated ring CH type finger 1) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the

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