ATRIP Polyclonal Antibody, 100ul[BT-AP00755] Palm Micro Centrifuges Proto-oncogene Wnt-1 have been implicated

Proto-oncogene Wnt-1 have been implicated in oncogenesis and in several developmental processes

they have not been fully characterized

The encoded protein is found to be associated with centromeres of mitotic HeLa cells| which suggests that this protein is a functional homolog of yeast Nuf2

which contains one ubiquitin-like domain

Isoform 4 belongs to a complex together with AMY1| AKAP1 and PRKAR2B

ATRIP Polyclonal Antibody, 100ul[BT-AP00755] Palm Micro Centrifuges Proto-oncogene Wnt-1 have been implicatedATRIP encodes an essential component of the DNA damage checkpoint. The encoded protein (ATR interacting protein) binds to single stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.