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Phospho-AIRE-1 (S156) Polyclonal Antibody, 100ul Liquid Handling &Storage similarity:Contains 1 SH3 domain

SKU: 35113660564

4.8
EUR141.00 EUR181.00

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Phospho-AIRE-1 (S156) Polyclonal Antibody, 100ul Liquid Handling &Storage similarity:Contains 1 SH3 domainAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and

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Description

similarity:Contains 1 SH3 domain

This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions

probably playing a role in regulating LPS-dependent monocyte responses

Inhibitor of PPP1CA

The protein directly targets mitochondria and causes apoptotic changes

Phospho-AIRE-1 (S156) Polyclonal Antibody, 100ul Liquid Handling &Storage similarity:Contains 1 SH3 domainAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and

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