MZF-1 Polyclonal Antibody, 100ul Biochemical Reagents Studies in mice suggest that

Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin| but not for the differentiation of pancreatic polypeptide-producing cells

but there is evidence that cells may not be able to engage in both activities at the same time

Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis

and regulates their signaling activities

Mutations in this gene are a cause of colorectal cancer (CRC)

MZF-1 Polyclonal Antibody, 100ul Biochemical Reagents Studies in mice suggest thatMZF1 is a Protein Coding gene. Myeloid Zinc Finger 1 binds to target promoter DNA and functions as trancription regulator. Regulates transcription from the PADI1 and CDH2 promoter. May be one regulator of transcriptional events during hemopoietic development. Gene Ontology (GO) annotations related to MZF1 include transcription factor activity, sequence specific DNA binding and RNA polymerase II core promoter proximal region sequence specific DNA