JAK2 Polyclonal Antibody, 100ul[BT-AP04689] Pathway and Network Analysis The Cdc42 guanine nucleotide exchange

The Cdc42 guanine nucleotide exchange factor 9 encoded by ARHGEF9 is a Rho-like GTPase that switches between the active (GTP-bound) state and inactive (GDP-bound) state to regulate CDC42 and other genes

The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins

a neuronal protein that plays a role in axonal development

|tissue specificity:Skeletal muscle| liver| heart and kidney

The receptor for this protein is RON tyrosine kinase

JAK2 Polyclonal Antibody, 100ul[BT-AP04689] Pathway and Network Analysis The Cdc42 guanine nucleotide exchangeTyrosine protein kinase JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.