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Histone H2A.Z (Acetyl Lys12) Rabbit Polyclonal Antibody, 50ul PCR Series This gene is a candidate

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Histone H2A.Z (Acetyl Lys12) Rabbit Polyclonal Antibody, 50ul PCR Series This gene is a candidateVariant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone

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Description

This gene is a candidate gene for cleft palate

This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1

Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers

Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases

The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes

Histone H2A.Z (Acetyl Lys12) Rabbit Polyclonal Antibody, 50ul PCR Series This gene is a candidateVariant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone

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