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PFKM Polyclonal Antibody, 50ul CellSafe™ BMP6 (bone morphogenetic protein 6)

SKU: 39246656514

4.8
USD162.00 USD189.00

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PFKM Polyclonal Antibody, 50ul CellSafe™ BMP6 (bone morphogenetic protein 6)Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose 6 phosphate to fructose 1,6 bisphosphate. Tetramer composition varies depending on tissue type. PFKM encodes the muscle type isozyme. Mutations in PFKM have been associated with glycogen storage disease type VII, also known as Tarui disease.

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Description

BMP6 (bone morphogenetic protein 6) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins

The encoded enzyme is responsible for the metabolism of prostaglandins| which function in a variety of physiologic and cellular processes such as inflammation

it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins

Serum level of this protein

Intermediate filamentents| along with microtubules and actin microfilaments| make up the cytoskeleton

PFKM Polyclonal Antibody, 50ul CellSafe™ BMP6 (bone morphogenetic protein 6)Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose 6 phosphate to fructose 1,6 bisphosphate. Tetramer composition varies depending on tissue type. PFKM encodes the muscle type isozyme. Mutations in PFKM have been associated with glycogen storage disease type VII, also known as Tarui disease.

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