Rabbit Caspase 3, CASP3 ELISA Kit, 96T sgRNA Oligos PubMed: 11884399

PubMed: 11884399

Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents

and a C-terminal substrate-binding domain

This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation

SRRM1 and THOC4

Rabbit Caspase 3, CASP3 ELISA Kit, 96T sgRNA Oligos PubMed: 11884399Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP ribose) polymerase (PARP) at a '216 Asp Gly 217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix loop helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase 6, 7 and 9. Involved in the cleavage of huntingtin.