EPAS-1 Polyclonal Antibody, 50ul Cell Labeling & Imaging This protein is also a

This protein is also a receptor for the complement component 3 fragments C3b and iC3b

This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL)| and in addition to a role in adhesion| it may serve as an accessory molecule for IEL activation

This gene encodes an alpha isoform of the constant regulatory subunit A

The type I isoform encoded by ARG1

It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides

EPAS-1 Polyclonal Antibody, 50ul Cell Labeling & Imaging This protein is also aEPAS1 encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The endothelial PAS domain protein 1 contains a basic helix loop helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.