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Researchers enrolled 17,604 adults who: were 45 years or older had overweight or obesity (BMI 27) already had heart disease (such as a prior heart attack, stroke, or peripheral artery disease) did not have diabetes Participants were randomly assigned to receive either: semaglutide 2.4 mg weekly, or a placebo (an injection with no active medication) They were followed for about 40 months (over 3 years)

These are the main side effects, but not every potential one

However, further investigations are needed to validate the above hypothesis

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14211442, doi:10.1007/s00394-013-0511-0, PMID 23508457

The ruling prevents compounding pharmacies from continuing to make copies of the popular weight-loss medications, which they had been permitted to do under FDA rules during the declared shortage