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CDKL5 Polyclonal Antibody, 50ul Cell Function Analysis GO annotations related to this

SKU: 44385305976

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CDKL5 Polyclonal Antibody, 50ul Cell Function Analysis GO annotations related to thisThis gene is a member of Ser Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X linked infantile spasm syndrome (ISSX), also known as X linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized.

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Description

GO annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity

The chimeric transcript is an in-frame fusion of NUP98 exon 8 to PSIP1/LEDGF exon 4

Tyrosine kinase growth factor receptors activate mitogen-activated protein kinases which then translocate into the nucleus and phosphorylate nuclear targets

Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription

Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 contains a conserved IMD

CDKL5 Polyclonal Antibody, 50ul Cell Function Analysis GO annotations related to thisThis gene is a member of Ser Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X linked infantile spasm syndrome (ISSX), also known as X linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized.

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