Histone H4 (Tri Methyl Lys21) Rabbit Polyclonal Antibody, 50ul Culture Tubes Mutations in this gene have

Mutations in this gene have been associated with Sertoli cell-only syndrome and male infertility

This transporter also transports aspartate

The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase

The protein associates with hamartin in a cytosolic complex| possibly acting as a chaperone for hamartin

and possibly in chromatin structure modification

Histone H4 (Tri Methyl Lys21) Rabbit Polyclonal Antibody, 50ul Culture Tubes Mutations in this gene haveCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation DNA repair DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones also called histone code and nucleosome remodeling. PTM: Acetylation at