Human Tumor Necrosis Factor Receptor Superfamily Member 14, TNFRSF14 ELISA Kit, 96T Pipette Controller and type IV pili of

and type IV pili of pathogenic Neisseria

Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28 (PubMed: 17294403)

Two additional variants have been described| but their full length sequences have not been determined

The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain

but not through a direct interaction with viral proteins

Human Tumor Necrosis Factor Receptor Superfamily Member 14, TNFRSF14 ELISA Kit, 96T Pipette Controller and type IV pili ofReceptor for four distinct ligands: The TNF superfamily members TNFSF14 LIGHT and homotrimeric LTA lymphotoxin alpha and the immunoglobulin superfamily members BTLA and CD160, altogether defining a complex stimulatory and inhibitory signaling network (PubMed: 9462508, PubMed: 10754304, PubMed: 18193050, PubMed: 23761635). Signals via the TRAF2 TRAF3 E3 ligase pathway to promote immune cell survival and differentiation (PubMed: 19915044, PubMed: