Progesterone Receptor(Phospho-Ser345) Rabbit Polyclonal Antibody, 100ul Enzyme Activity Assays The breast cancer susceptibility gene

The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q

The gene maps to a region of 19q13

The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors

but translocates to the cytoplasm at the start of S phase

CD164 (CD164 molecule) is a type I integral transmembrane sialomucin that functions as an adhesion receptor

Progesterone Receptor(Phospho-Ser345) Rabbit Polyclonal Antibody, 100ul Enzyme Activity Assays The breast cancer susceptibility geneThis gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants both protein coding and non protein coding. Two of the isoforms (A and B) are