Jagged1 Polyclonal Antibody, 100ul[BT-AP10553] Liquid Handling ＆Storage The protein encoded by this

The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product

It is an orphan receptor

|Contains 2 cystatin domains

It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another

Alternative splicing has been observed for this gene

Jagged1 Polyclonal Antibody, 100ul[BT-AP10553] Liquid Handling ＆Storage The protein encoded by thisThe jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis.