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HLA-DQB1/2 Polyclonal Antibody, 50ul Measuring Instruments Each of the remaining nine

SKU: 4854050935

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HLA-DQB1/2 Polyclonal Antibody, 50ul Measuring Instruments Each of the remaining nineHLA DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: b lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28 kDa and it

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Description

Each of the remaining nine 5' exons may be spliced to the four common exons| resulting in nine proteins with different N-termini and identical C-termini

a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination

The encoded protein acts as a chaprone in signaling downstream of TGF-beta

The protein was also shown to inhibit the accumulation of cyclin D1

Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease

HLA-DQB1/2 Polyclonal Antibody, 50ul Measuring Instruments Each of the remaining nineHLA DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: b lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26 28 kDa and it

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