Rat Caspase-2, CASP2 ELISA Kit, 96T Endonucleases & Exonucleases Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include calmodulin binding and Ras GTPase binding

leading to the recruitment of TIR-containing downstream adapter MYD88 through homotypic interaction

such as GABARAP1L

member 4) family member in the same cluster

This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family

Rat Caspase-2, CASP2 ELISA Kit, 96T Endonucleases & Exonucleases Gene Ontology (GO) annotations relatedInvolved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival (By similarity). Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress (By similarity).