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Erbin Rabbit Polyclonal Antibody, 20ul[BT-AP09695] Antisense Oligonucleotides OPN4 encodes a photoreceptive opsin

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Erbin Rabbit Polyclonal Antibody, 20ul[BT-AP09695] Antisense Oligonucleotides OPN4 encodes a photoreceptive opsinThis gene is a member of the leucine rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Description

OPN4 encodes a photoreceptive opsin protein melanopsin that is expressed within the ganglion and amacrine cell layers of the retina

Besides the central nervous system

GJA1 is a member of the connexin gene family

This protein may regulate neuronal proliferation and has been implicated in the progression of glioblastoma through its ability to dephosphorylate the p53 tumor suppressor

Btk is necessary for proper B cell development

Erbin Rabbit Polyclonal Antibody, 20ul[BT-AP09695] Antisense Oligonucleotides OPN4 encodes a photoreceptive opsinThis gene is a member of the leucine rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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