JMJD2B Polyclonal Antibody, 20ul Miscellaneous Increases firing activity and intracellular

Increases firing activity and intracellular calcium oscillations in luteinizing hormone-releasing hormone (LHRH) neurons

while loss of heterozygosity of DMTN is thought to play a role in prostate cancer progression

it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

There is a pseudogene for ALMS1 located adjacent in the same region of chromosome 2

This protein acts as a sequence-specific repressor of transcription

JMJD2B Polyclonal Antibody, 20ul Miscellaneous Increases firing activity and intracellularHistone demethylase that specifically demethylates 'Lys 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys 4', H3 'Lys 27', H3 'Lys 36' nor H4 'Lys 20'. Only able to demethylate trimethylated H3 'Lys 9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.