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UN13B Rabbit Polyclonal Antibody, 20ul Peripheral Blood Separation Tube ADP-ribosylation factor (ARF)-like proteins (ARLs)

SKU: 5230583673

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UN13B Rabbit Polyclonal Antibody, 20ul Peripheral Blood Separation Tube ADP-ribosylation factor (ARF)-like proteins (ARLs)This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog and contains 3 C2 domains and a diacylglycerol binding C1 domain. Hyperglycemia increases the levels of diacylglycerol which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other

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Description

ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases

and proteolytic processing significantly affect the activity of this protein

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An important paralog of this gene is GPR179

It involves in translation termination in response to the termination codons UAA

UN13B Rabbit Polyclonal Antibody, 20ul Peripheral Blood Separation Tube ADP-ribosylation factor (ARF)-like proteins (ARLs)This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog and contains 3 C2 domains and a diacylglycerol binding C1 domain. Hyperglycemia increases the levels of diacylglycerol which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other

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