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Phospho-B23 (T199) Polyclonal Antibody, 20ul Protein Post-translational Modification The mitogen-activated protein kinase 8

SKU: 52657352443

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Phospho-B23 (T199) Polyclonal Antibody, 20ul Protein Post-translational Modification The mitogen-activated protein kinase 8NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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Description

The mitogen-activated protein kinase 8 interacting protein 2 encoded by MAPK8IP2 is closely related to MAPK8IP1/IB1/JIP-1

One isoform lacks the intermembrane region and is secreted outside the cell

Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN)

100% undergone for production line air tightness test

a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11

Phospho-B23 (T199) Polyclonal Antibody, 20ul Protein Post-translational Modification The mitogen-activated protein kinase 8NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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