LPIN2 Polyclonal Antibody, 20ul Pasteur Pipets Each of the three genes

Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein

The protein encoded by TSG101 (tumor susceptibility 101) belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes

and a single representative of the other 3

The protein encoded by LIG4 is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction

which was isolated and identified based on its enzymatic activity and amino acid sequence

LPIN2 Polyclonal Antibody, 20ul Pasteur Pipets Each of the three genesMouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism. This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance.