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POLH Polyclonal Antibody, 100ul Custom RNA Oligos Androgen-induced 1 (AIG1) is a

SKU: 5547850240

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POLH Polyclonal Antibody, 100ul Custom RNA Oligos Androgen-induced 1 (AIG1) is aThis gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA directed polymerases. However, it accurately replicates UV damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV induced DNA damage. This polymerase is thought to be

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Description

Androgen-induced 1 (AIG1) is a novel Pirh2-interacting protein

and barely detectable level in the peripheral leukocytes

It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction

The expression of this gene appears to be restricted to spermatocytes

More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene

POLH Polyclonal Antibody, 100ul Custom RNA Oligos Androgen-induced 1 (AIG1) is aThis gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA directed polymerases. However, it accurately replicates UV damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV induced DNA damage. This polymerase is thought to be

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