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PAK gamma(Phospho Ser20) Polyclonal Antibody, 50ul Cell Screening and Imaging Cleavage of the alpha chain

SKU: 57542847900

4.8
USD162.00 USD191.00

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PAK gamma(Phospho Ser20) Polyclonal Antibody, 50ul Cell Screening and Imaging Cleavage of the alpha chainThe p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, and may play a role

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Description

Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin

The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene

which regulate movement of solutes and ions through the paracellular space

MED8 encodes a protein component of the mediator complex

Among its related pathways are Gene Expression and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3

PAK gamma(Phospho Ser20) Polyclonal Antibody, 50ul Cell Screening and Imaging Cleavage of the alpha chainThe p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, and may play a role

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