RGMC Polyclonal Antibody, 50ul Endonucleases & Exonucleases The encoded protein is a

The encoded protein is a substrate for cGMP-dependent protein kinase

a role in kidney and muscle development is indicated

but shuttles into the nucleus where it localizes to nuclear speckles

These mice are also resistant to diet-induced obesity and diabetes

gene regulation

RGMC Polyclonal Antibody, 50ul Endonucleases & Exonucleases The encoded protein is aThe product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Two uORFs in the 5' UTR negatively regulate the expression and activity of the encoded protein. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in