CUL7 Polyclonal Antibody, 20ul Cell Culture Dishes AMPK is a cellular energy

AMPK is a cellular energy sensor conserved in all eukaryotic cells

and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1)

Members of this family are involved in a variety of cellular processes

a single transmembrane segment and two tandem intracytoplasmic catalytic domains

and reduction in gene expression was shown in colorectal cancers (PMID: 17982127)

CUL7 Polyclonal Antibody, 20ul Cell Culture Dishes AMPK is a cellular energyThe protein encoded by this gene is a component of an E3 ubiquitin protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in this gene are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for this gene.