SnoN Polyclonal Antibody, 50ul Molecular Biology on insulin receptor signaling
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SnoN Polyclonal Antibody, 50ul Molecular Biology on insulin receptor signalingSki like protein encoded by SKIL is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding
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