LC3B Polyclonal Antibody, 50ul Immunoassays Mutations of this gene have

Mutations of this gene have been associated with variety of inherited chondrodysplasias

Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore

This gene affects the sensitivity of tumor cells to adenovirus infection

A minor proportion is also found at nuclear pore complexes and around the pericentriolar matrix of mitotic centromeres

The encoded kinase (casein kinase 1 gamma 1) plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin

LC3B Polyclonal Antibody, 50ul Immunoassays Mutations of this gene haveThe product of this gene is a subunit of neuronal microtubule associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.