DBLOH Polyclonal Antibody, 50ul Filtration The Ser/Thr protein kinase encoded

The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily

Contains 1 B30

Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216)

tissue specificity:Expressed in lung fibroblasts

Molecular diagnosis involves using nucleic acids or proteins as biomarkers to help diagnose and treat diseases more effectively

DBLOH Polyclonal Antibody, 50ul Filtration The Ser/Thr protein kinase encodedThis gene encodes an inhibitor of apoptosis protein (IAP) binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young adult onset of nonsyndromic deafness 64. Alternative splicing results in multiple transcript