FBX18 Rabbit Polyclonal Antibody, 50ul Gel & Buffers May play an important role

May play an important role in the developing brain and neuronal differentiation

which belong to the recoverin branch of the EF-hand superfamily

considered an open rectifier

but also as a potent signalling molecule

Mutations in this gene cause Alexander disease

FBX18 Rabbit Polyclonal Antibody, 50ul Gel & Buffers May play an important roleThis gene encodes a member of the F box protein family members of which are characterized by an approximately 40 amino acid motif the F box. The F box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1 cullin F box) which function in phosphorylation dependent ubiquitination. The F box proteins are divided into three classes: Fbws containing WD 40 domains Fbls containing leucine rich repeats and Fbxs