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gp91-phox Polyclonal Antibody, 100ul[BT-AP03657] High Speed Micro-Centrifuges Mutations in this gene can

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gp91-phox Polyclonal Antibody, 100ul[BT-AP03657] High Speed Micro-Centrifuges Mutations in this gene canCytochrome b ( 245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic

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Description

Mutations in this gene can cause combined oxidative phosphorylation deficiency 14 (Alpers encephalopathy)

The encoded protein is also able to release NEDD8| a ubiquitin-like protein| from NEDD8-conjugated proteins

The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases

The product of this gene is a transmembrane protein that is differentially expressed in many cancer cells

gp91-phox Polyclonal Antibody, 100ul[BT-AP03657] High Speed Micro-Centrifuges Mutations in this gene canCytochrome b ( 245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic

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