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Survivin(Phospho Thr34) Polyclonal Antibody, 50ul Cell Culture Flasks Mutations in this gene have

SKU: 6535477418

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Survivin(Phospho Thr34) Polyclonal Antibody, 50ul Cell Culture Flasks Mutations in this gene haveThis gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues.

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Description

Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH)

FATPs are involved in the uptake of long-chain fatty acids and have unique expression patterns

Expression of this gene is induced by cold shock and low oxygen tension

becomes associated with mitotic spindles in a highly dynamic manner during mitosis

alternative products:Experimental confirmation may be lacking for some isoforms|Catalytic activity:Hydrolysis of alkylated DNA| releasing 3-methyladenine| 3-methylguanine| 7-methylguanine and 7-methyladenine

Survivin(Phospho Thr34) Polyclonal Antibody, 50ul Cell Culture Flasks Mutations in this gene haveThis gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues.

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