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4E-BP1 Polyclonal Antibody, 50ul[BT-AP00035] Miscellaneous Three isoforms of ZFYVE19 exist

SKU: 65383566257

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4E-BP1 Polyclonal Antibody, 50ul[BT-AP00035] Miscellaneous Three isoforms of ZFYVE19 existEIF4EBP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV

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Description

Three isoforms of ZFYVE19 exist due to alternative splicing events

Alternative splicing of TOP2B results in two transcript variants

Since this protein is not capable of binding DNA directly

shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases

ANAPC1 (anaphase promoting complex subunit 1) encodes a subunit of the anaphase-promoting complex

4E-BP1 Polyclonal Antibody, 50ul[BT-AP00035] Miscellaneous Three isoforms of ZFYVE19 existEIF4EBP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV

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