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Cdc25B(Phospho Ser323) Polyclonal Antibody, 100ul PCR Series and is involved in the

SKU: 66282641940

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Cdc25B(Phospho Ser323) Polyclonal Antibody, 100ul PCR Series and is involved in theCDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in

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Description

and is involved in the regulation of fat metabolism

resulting from the use of alternate downstream translation initiation sites

Multiple transcript variants encoding different isoforms have been described

Exon 1 encodes the leader peptide| exons 2 and 3 encode the two extracellular domains| exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail

It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis

Cdc25B(Phospho Ser323) Polyclonal Antibody, 100ul PCR Series and is involved in theCDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in

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