Rat Glypican-3, GPC-3 ELISA Kit, 96T Electronic Pipette May play a role in

May play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity

This gene is widely expressed in many tissues with the greatest abundance in brain and testis

mitotic checkpoint protein) contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein

Required for proper attachment of the midbody to the cell membrane during cytokinesis

May play a role in the maturation and maintenance of the blood-brain barrier (By similarity)

Rat Glypican-3, GPC-3 ELISA Kit, 96T Electronic Pipette May play a role inCell surface proteoglycan that bears heparan sulfate (By similarity). Negatively regulates the hedgehog signaling pathway when attached via the GPI anchor to the cell surface by competing with the hedgehog receptor PTC1 for binding to hedgehog proteins (By similarity). Binding to the hedgehog protein SHH triggers internalization of the complex by endocytosis and its subsequent lysosomal degradation (By similarity). Positively regulates the canonical