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VRK1 Polyclonal Antibody, 100ul Insect Expression Abnormal recombination between PRKX and

SKU: 67612705920

4.1
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VRK1 Polyclonal Antibody, 100ul Insect Expression Abnormal recombination between PRKX andThis gene encodes a member of the vaccinia related kinase (VRK) family of serine threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate

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Description

Abnormal recombination between PRKX and a related pseudogene on chromosome Y is a frequent cause of sex reversal disorder in XX males and XY females

The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators

Skeletal Muscle) is a Protein Coding gene

Binding of 53BP1 to the L3 loop of p53 and of 53BP2 to the L2 loop of p53 confirms that the loop is dependent on p53 conformation

The enzyme may be involved in several physiological processes including cell contraction

VRK1 Polyclonal Antibody, 100ul Insect Expression Abnormal recombination between PRKX andThis gene encodes a member of the vaccinia related kinase (VRK) family of serine threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate

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