CD6 Polyclonal Antibody, 100ul[BT-AP01961] Culture Media Transcriptional repression by the encoded
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CD6 Polyclonal Antibody, 100ul[BT-AP01961] Culture Media Transcriptional repression by the encodedKLKB1 encodes a glycoprotein that participates in the surface dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations
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