Hox-B9 Polyclonal Antibody, 50ul ADME The encoded protein contains a

The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles

the encoded protein binds to the ER stress response element

A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity

Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene

a nucleation core

Hox-B9 Polyclonal Antibody, 50ul ADME The encoded protein contains aHOXB9 is a member of the Abd B homeobox family and encodes a protein with a homeobox DNA binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. Homeobox protein Hox B9 functions as a sequence specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer.