RIN2 Polyclonal Antibody, 100ul Buffer Solutions CCR6 is preferentially expressed by

CCR6 is preferentially expressed by immature dendritic cells and memory T cells

These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex

The major encoded protein product

DNA ligase 3 encoded by LIG3 is involved in excision repair and is located in both the mitochondria and nucleus

Also expressed in certain liver and kidney carcinomas

RIN2 Polyclonal Antibody, 100ul Buffer Solutions CCR6 is preferentially expressed byThe RAB5 protein is a small GTPase involved in membrane trafficking in the early endocytic pathway. The protein encoded by this gene binds the GTP bound form of the RAB5 protein preferentially over the GDP bound form, and functions as a guanine nucleotide exchange factor for RAB5. The encoded protein is found primarily as a tetramer in the cytoplasm and does not bind other members of the RAB family. Mutations in this gene cause macrocephaly alopecia