Raf-1(Phospho Ser621) Polyclonal Antibody, 20ul Cell Culture PTEN (phosphatase and tensin homolog)

PTEN (phosphatase and tensin homolog) was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency

RPS6KA1 (ribosomal protein S6 kinase A1) encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases

This enzyme cleaves amino-terminal propeptides from type I procollagen

C-terminal

which results in a fusion protein

Raf-1(Phospho Ser621) Polyclonal Antibody, 20ul Cell Culture PTEN (phosphatase and tensin homolog)This gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.