Mnk1 Polyclonal Antibody, 100ul[BT-AP05496] Antibodies It is not currently known

It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome

Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression| and the zinc-fingers comprise the DNA binding domain

and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function

and nervous system development and function

It plays a role in mediating cell fate decisions during hematopoiesis

Mnk1 Polyclonal Antibody, 100ul[BT-AP05496] Antibodies It is not currently knownMKNK1 (MAP kinase interacting serine threonine kinase 1) encodes a Ser Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C terminal region of eIF4G. Alternatively spliced transcript variants have been noted for MKNK1.