NDUB7 Polyclonal Antibody, 20ul Drying & Desiccation This locus encodes a member

This locus encodes a member of the MADS box transcription enhancer factor 2 (MEF2) family of proteins

and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease

The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1

This protein also functions as a co-activator of the transcriptional activator p63

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NDUB7 Polyclonal Antibody, 20ul Drying & Desiccation This locus encodes a memberThe protein encoded by this gene is a subunit of the multisubunit NADH: ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It is located at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.