IKappaB- Alpha Polyclonal Antibody, 50ul[BT-AP04676] Centrifuges TNNI3K encodes a protein that

TNNI3K encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases

Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover

which is required for the activation of the alpha-aminoadipate dehydrogenase in the biosynthetic pathway of lysine

The gene is located about 11kb downstream of the integrin subunit alpha X gene

Potential poly-A sequence starting in position 409

IKappaB- Alpha Polyclonal Antibody, 50ul[BT-AP04676] Centrifuges TNNI3K encodes a protein thatNFKBIA encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell