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Btk Polyclonal Antibody, 50ul[BT-AP01004] Oligo Pool Multiple alternatively spliced transcript variants

SKU: 73224127348

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SEK162.00 SEK189.00

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Btk Polyclonal Antibody, 50ul[BT-AP01004] Oligo Pool Multiple alternatively spliced transcript variantsTyrosine protein kinase BTK encoded by BTK plays a crucial role in B cell development. Mutations in this gene cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

Multiple alternatively spliced transcript variants were described| but the full-length sequence of only some were determined

Mitogen-activated protein kinase kinase kinase MLT

denoted as AGTR1B

This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain

neurite elongation and neuronal migration

Btk Polyclonal Antibody, 50ul[BT-AP01004] Oligo Pool Multiple alternatively spliced transcript variantsTyrosine protein kinase BTK encoded by BTK plays a crucial role in B cell development. Mutations in this gene cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.

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