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CD56 Polyclonal Antibody, 50ul[BT-AP01633] Metabolic enzymes Two alternatively spliced transcript variants

SKU: 73781439933

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CD56 Polyclonal Antibody, 50ul[BT-AP01633] Metabolic enzymes Two alternatively spliced transcript variantsCDK5RAP2 (CDK5 regulatory subunit associated protein 2) encodes a regulator of CDK5 (cyclin dependent kinase 5) activity. The protein encoded by CDK5RAP2 is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.

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Description

Two alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene

and sister chromatid separation

Expressed at lower level in neural tissues and at the highest level in the adrenal gland

such as E2F7

Increases p53/TP53-dependent transcription and apoptosis

CD56 Polyclonal Antibody, 50ul[BT-AP01633] Metabolic enzymes Two alternatively spliced transcript variantsCDK5RAP2 (CDK5 regulatory subunit associated protein 2) encodes a regulator of CDK5 (cyclin dependent kinase 5) activity. The protein encoded by CDK5RAP2 is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.

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